Note: This thread is related to #Coronavirus #COVID19

Follow the World Health Organization's instructions to reduce your risk of infection:

1/ Frequently clean hands by using alcohol-based hand rub or soap and water.

2/ When coughing and sneezing cover mouth and nose with flexed elbow or tissue - throw issue away immediately and wash hands.

3/ Avoid close contact with anyone that has fever and cough.

Florian Krammer @florian_krammer Viruses, viruses, viruses and vaccines Professor at the Department of Microbiology Icahn School of Medicine at Mount Sinai Feb. 28, 2020 1 min read

THREAD/1: We saw now several reports of reinfection and I wanted to talk a little about that. While immunity induced by SARS-CoV-1, MERS-CoV and human CoVs is not very long lived, an immune response is typically induced and antibodies persist for 1-3 years.

2) Now, there is evidence that people with COVID19 mount an immune response (e.g.  https://www.medrxiv.org/content/10.1101/2020.02.20.20025841v1 ). That makes re-infection, especially short-term extremely unlikely. What is more likely is, that the patient is still shedding virus but some of the tests were negative.

3) Follow up tests can turn positive after a few negative tests, e.g. because sampling was better. Also, and this is a very important point, just because somebody still tests positive in a nucleic acid based test, does not mean they are still shedding infectious virus.

4) E.g. Measles RNA can be detected for months in patients, long after infectious virus shedding has stopped. This is also the case for other viruses. And I think this is the most likely scenario here.


You can follow @florian_krammer.



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