Natalie E. Dean, PhD+ Your Authors @nataliexdean Assistant Professor of Biostatistics at @UF specializing in emerging infectious diseases and vaccine study design. @HarvardBiostats PhD. Tweets my own. She/her. Apr. 11, 2020 1 min read + Your Authors

In considering different pandemic plans, @paulmromer presents an interesting strategy. Test asymptomatic people at a scale previously thought impossible.

I had a little💡moment today. This strategy already exists for HIV. It is called “test-and-treat.”

 https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(08)61697-9/fulltext 

In test-and-treat, the goal is to achieve routine, universal HIV testing in communities. HIV positive individuals are immediately put on antiretrovirals to suppress viral load and prevent onward transmission.

The parallels between this and @paulmromer’s plan are immediate, with treatment being replaced with isolation. Test-and-isolate. We can draw upon the available HIV modeling literature to examine this further.

Importantly, though, even while we pursue test-and-treat for HIV control, we have not stopped other control strategies. The reality is that test-and-treat is difficult, so it is used in combination with other interventions (condom use, circumcision, linkage to care).

I believe the best way forward is an ambitious, multi-pronged strategy, with massive testing plus tracing and voluntary options for isolation. It will take a lot of work and coordination, but it is vital.

A link to his plan.


You can follow @nataliexdean.



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