Ashish K. Jha+ Your Authors @ashishkjha Physician, researcher, and advocate for the notion that an ounce of data is worth a thousand pounds of opinion. Director @harvardgh. Soon, Dean @Brown_SPH Jun. 29, 2020 1 min read + Your Authors

New important paper in @NEJM

At least 186 kids in US hospitals with Multisystem Inflammatory Syndrome in Children (MIS-C) over a 2 month period.

Most had documented infection with SARS-CoV2

Some really important key findings included....

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 https://www.nejm.org/doi/full/10.1056/NEJMoa2021680 

1. Most of these kids were previously healthy

2. median age was 8.3 years old

3. 80% of kids had cardiovascular complications

4. 80% of kids were in ICU

5. 20% of kids required mechanical ventilation

And finally, heartbreakingly, 2% of kids died

2/3

Most of the kids received steroids, immunoglobulins

And obviously, thankfully, most recovered although long-term effects are not known.

Conclusion (from authors):

"MIS-C associated with SARS-CoV2 led to serious and life-threatening illness in previously healthy children"

3/4

Bottom line

We don't understand the long-term issues with the virus.

It clearly is not totally benign in any population

Let's be less cavalier about letting young people get infected

We need to continue to reduce infections and protect people until we have a vaccine.

Fin


You can follow @ashishkjha.



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