New study out on the mRNA-1273 vaccine in @NEJM and its more good news.
Its a study in non-human primates -- a challenge study where primates were vaccinated, then challenged with the virus.
So what did they find?
As I said, good news.
24 rhesus macques were innoculated with one of two doses of the vaccine
They all developed (especially at the higher doses) neutralizing antibodies
And developed t-cell responses.
More robust in the higher dose
But there's more!
When subsequently challenged by SARS-CoV2, small number of macques had any detectable virus
None developed severe illness
More evidence that m-RNA vaccines will likely work
We obviously still need to await phase 3 trials
But I'm optimistic we will have a vaccine in 2021
You can follow @ashishkjha.
Tip: mention @threader_app on a Twitter thread with the keyword “compile” to get a link to it.
Enjoy Threader? Sign up.
Since you’re here...
... we’re asking visitors like you to make a contribution to support this independent project. In these uncertain times, access to information is vital. Threader gets 1,000,000+ visits a month and our iOS Twitter client was featured as an App of the Day by Apple. Your financial support will help two developers to keep working on this app. Everyone’s contribution, big or small, is so valuable. Support Threader by becoming premium or by donating on PayPal. Thank you.